Tuesday, November 15, 2005

Combining two new drugs - UCN-01 and MEK 1/2 -may offer breast cancer hope

DeHavilland, November 15, 2005
Combining two new drugs (UCN-01 and MEK 1/2, a protein inhibitor found to block tumour survival pathways) has been shown to kill up to 3/4 of breast tumours in mice and prevent tumours from re-growing. Separately, they killed only a tiny percentage of cancerous cells. These drugs are also part of a modern class of drugs that are less toxic to non-cancerous cells. Three researchers operated the same studies independently and all found similar results. The authors say more research is needed to test the effectiveness of the drug on humans.

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