Friday, January 27, 2006

BRCA1 Gene Found To Inhibit Both Estrogen And Progesterone

Georgetown University Medical Center, January 26, 2006
It’s been known that the breast cancer susceptibility gene BRCA1 regulates use of estrogen in breast and other cells, but now researchers at Georgetown University Medical Center have discovered that it also controls activity of a second sex steroid hormone, progesterone.
The findings, conducted in cell culture and in mice and reported by the researchers in the January issue of Molecular Endocrinology, could help explain why women who have mutations in their BRCA1 gene are susceptible to a number of different “hormone-dependent” cancers, including those of the breast, endometriun and cervix. --Click the title of this post to read the full article from its source--

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