Monday, January 09, 2006

Cell Stress Protein Linked To Aggressive Breast Cancer

Northwestern University, January 4, 2006
A groundbreaking study led by Northwestern University researchers has demonstrated that a protein called alphaB-crystallin, which normally protects cells from stress damage, triggers events that may cause breast cancer when overactive. Breast cancer is the most common cancer in women and is responsible for over 400,000 deaths annually in women throughout the world. Most of these deaths are the result of aggressive breast tumors that often fail to respond to current treatments. The researchers found that women whose breast tumors express the alphaB-crystallin protein have a shorter survival, suggesting that alphaB-crystallin may be a useful molecular marker to identify women with aggressive breast cancer and to develop new targeted cancer therapies. The study was published in the January issue of the Journal of Clinical Investigation. --Click the title of this post to read the full article from its source--

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