Monday, January 23, 2006

Endogenous Sex Hormones May Not Predict Breast Cancer Risk

Martha Kerr, The Cancer Page (via Reuters Health), January 23, 2006
The endogenous sex hormone levels of some women at high risk for breast cancer may paint a false picture of that risk, according to findings published in the January 18th issue of the Journal of the National Cancer Institute (Journal of the National Cancer Institute 2006;98:110-15). Lead investigator Dr. Mary S. Beattie of the University of California, San Francisco, and colleagues measured estradiol, testosterone and sex hormone-binding globulin in plasma samples taken from a study group of 135 women with postmenopausal breast cancer and 275 postmenopausal women without breast cancer who served as controls in the National Surgical Adjuvant Breast and Bowel Project Cancer Prevention Trial. Women had received tamoxifen or placebo for 69 months. Median plasma levels of estradiol, testosterone and sex hormone-binding globulin were similar in study patients and controls. --Click the title of this post to read the full article from its source--

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