Sunday, January 15, 2006

Researchers discover protein fragment that helps predict breast cancer outcome

EurekAlert, January 15, 2006
Oregon Health & Science University Cancer Institute researchers have identified a protein fragment in some human breast cancers that may help predict a patient's chances of survival.
The presence of the fragment, called p95HER-2, in breast cancer tissue correlates closely with lymph node metastasis and earlier recurrence of the disease, suggesting that p95HER-2 is a marker and perhaps even involved in metastasis. "By studying this marker we have a better chance to identify the patients who are more likely to have a longer disease-free survival," said Edward Keenan, Ph.D., one of the authors of the study. Keenan is professor of physiology and pharmacology and associate dean for medical education, OHSU School of Medicine.

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