Wednesday, March 01, 2006

Gene Expression Profiling Allows Grade 2 Breast Cancer Patients To Be Reclassified Into Two Groups, March 01, 2006
A study published in the Journal of the National Cancer Institute reports that gene expression profiling may allow women with grade 2 breast cancer to be reclassified into two groups—one with a lower risk of recurrence and one with a higher risk of recurrence. The prognosis of women with breast cancer depends on several factors, including the grade of the tumor. Grade refers to how abnormal the tumor cells look under a microscope and how quickly the tumor is likely to grow. A commonly used grading system for breast cancer assigns grades of 1 to 3, with 1 being the least abnormal and 3 being the most abnormal. Many breast cancers are classified as grade 2, suggesting an intermediate level of risk. For women who fall into this group that is neither low-risk nor high-risk, there continues to be uncertainty about expected risk of cancer recurrence. To explore whether additional information about the tumor could help refine prognosis in women with grade 2 tumors, researchers evaluated the role of gene expression profiling. --Click the title of this post to read the full article from its source--


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