Friday, August 25, 2006

How cigarette smoke leads to breast cancer

University of Florida scientists have reported that cigarette smoke could turn normal breast cells cancerous by blocking their ability to repair themselves, eventually triggering tumour development. In the study, researchers exposed normal breast epithelial cells to cigarette smoke condensate-a tar and found the cells acquired the mutation characteristics of malignant cells. The researches found that DNA repair was compromised when chemical components of smoke activate a key gene. That gene interacts with an enzyme that plays a crucial role in repairing damaged DNA, preventing it from doing its job. The cell, despite its mutated form, can then multiply rapidly, triggering a tumour. --Click the title of this post to read the full article from its source--

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