Monday, August 28, 2006

Plastics Chemical Might Promote Breast Cancer

A chemical found in the harder plastics that make up CD cases, water-cooler jugs and other objects people handle might help promote breast cancer, researchers say. The chemical - a "pseudo-estrogen" called bisphenol-A - appears to be preferentially absorbed by breast tumor cells, according to a new study published in the Aug. 28 issue of Chemistry & Biology. While the new research doesn't give any definitive answer on BPA's potential role in breast cancer, American researchers say they have uncovered a biological mechanism that allows the compound to concentrate in tumor cells. Healthy cells don't readily absorb bisphenol sulfate, one of the body's metabolized forms of BPA. So, many experts have assumed the chemical might be harmless. However, "it turns out that breast tumor cells are different than normal cells," lead researcher Theodore Widlanski of Indiana University, said. "We showed that breast tumor cells actually convert bisphenol sulfate back into bisphenol-A, which can then be taken up into tumor cells." --Click the title of this post to read the full article from its source--


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