Tuesday, October 31, 2006

FDA OKs Bionovo breast cancer drug test

The Food and Drug Administration accepted Bionovo Inc.'s protocol for an early-stage clinical trial of BZL101, a drug for metastatic breast cancer. Emeryville-based Bionovo (OTCBB: BNVI) said Tuesday that the Phase I/II trial will be run at 10 centers in the United States. The company will enroll the first patients in the trial next year in the first quarter. --Click the title of this post to read the full article from its source--

Fat Stem Cells Being Studied As Option For Breast Reconstruction

Breast cancer survivors might one day avoid the prospect of invasive breast reconstruction surgery, opting instead for an approach that would involve using stem cells derived from their own fat, suggest University of Pittsburgh researchers who are studying the potential these cells may have for regenerating new breast tissue. In animal models, the researchers hope to prove that an injection of fat-derived stem cells that are seeded onto microscopic scaffold structures will enable the production of a durable, replacement soft tissue. The team, led by J. Peter Rubin, M.D., assistant professor of plastic and reconstructive surgery at the University of Pittsburgh School of Medicine, recently received a three-year grant from the National Cancer Institute to further explore this unique approach. --Click the title of this post to read the full article from its source--

New Study Warns Against Linking Ethnic Identity To Breast Cancer Genes

Genetic research over the past decade has linked Ashkenazi Jewish ethnicity to an increased risk for hereditary breast cancer, so much so that certain gene mutations have become known as "Jewish ancestral mutations." But a new study released in the November issue of The American Journal of Public Health challenges this approach, warning that disparities in access to care and other unintended consequences can, and have, resulted. --Click the title of this post to read the full article from its source--

Monday, October 23, 2006

Hormone Levels Linked with Premenopausal Breast Cancer

According to the results of a study published in the Journal of the National Cancer Institute, circulating levels of estrogen and testosterone during specific points in the menstrual cycle appear to influence breast cancer risk in premenopausal women. Many breast cancers are hormone responsive, prompting interest in the relationship between serum levels of hormones such as estrogen and the risk of breast cancer. While higher levels of circulating estrogens have been linked with an increased risk of breast cancer in postmenopausal women, less is known about the relationship between circulating hormone levels and breast cancer risk in premenopausal women. Studying the link between hormone levels and breast cancer risk can be challenging in premenopausal women because the levels of many hormones fluctuate over the course of the menstrual cycle. To explore the link premenopausal breast cancer and levels of circulating hormones, researchers evaluated information from the Nurses’ Health Study II. This study enrolled more then 100,000 female nurses who were between the ages of 25 and 42 when the study began in 1989. --Click the title of this post to read the full article from its source--

Thursday, October 19, 2006

41 Canadians join class-action bid on faulty breast-cancer tests

Forty-one women have so far come forward to ask the Newfoundland Supreme Court to certify a class-action lawsuit arising from errors made in testing tissue samples. The women are all breast cancer patients whose tissue samples had to be retested because of errors that were first disclosed in 2005. Some of the samples date as far back as 1997. The Eastern Health regional authority, which recently finished contacting women involved in the case, sent hundreds of samples to Mount Sinai Hospital in Toronto for retesting. Ches Crosbie, the St. John's lawyer who filed court papers this summer, said little information has been revealed about how many women received erroneous results from hormone receptor tests, which indicate what type of treatment is appropriate. "They haven't been given any information since a year ago about the rate of reversal, or error rate, if you want to call it that," Crosbie told CBC News. --Click the title of this post to read the full article from its source--

Sunday, October 15, 2006

Getting Male Breast Cancer On The Radar

Survivors, Doctors Want To Increase Disease Awareness. There's one group of breast cancer survivors many people don't even know they exist. Few people realize men can get breast cancer, too. --Click the title of this post to read the full article from its source--

Breast cancer farm workers 'link'

Women who have worked, or grown up, on a farm have a much higher risk of getting breast cancer, a study claims. Stirling University researchers said women who then worked in healthcare further increased their risk, although more research is needed to explain why. The study raises fresh concerns about the risk posed by weed killers and chemicals containing chlorine. However, Cancer Research UK said the study of 1,100 women was too small a group to draw any conclusions. --Click the title of this post to read the full article from its source--

Wednesday, October 04, 2006

The Other Breast Cancer That's Nothing But Silent

If there is one thing that the American Cancer Society wants to communicate to women is that they don't have to have a lump in their breast to have breast cancer.For years, generations of women were taught to look for a lump -- an obvious abnormal mass -- during breast self-examination -- followed by a mammogram and a doctor's visit.However, there has been another type of breast cancer lurking in the shadows for just as many years -- one that often has no lump, rarely shows up on a mammogram and spreads so rapidly that, once discovered, the chances of recovery are greatly reduced.Inflammatory Breast Cancer (IBC) is comparatively rare (about 5 percent of all cancers) and fast-spreading form of breast cancer. Diagnoses of the disease have increase during the past 20 years. News of its existance initially spread following a story broadcast by KOMO-TV in Seattle, warning of a "new" and "silent" killer. The original report generated a flurry of activity this summer. Millions of people downloaded the story and then they began to pass it along by e-mail to others.In the report, cancer victim Sue Asci said she thought the pain and discomfort was a sunburn. “I never thought cancer,” she said. --Click the title of this post to read the full article from its source--

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