Saturday, December 23, 2006

Treatment-Induced Amenorrhea May Prevent Breast Cancer Relapse: Presented at SABCS

Treatment-induced amenorrhea during chemotherapy for breast cancer is associated with a significant 44% reduction in relapse risk in women under 40 years of age, a prospective, randomized study shows.Michael Gnant, MD, professor of surgery, Medical University of Vienna, Austria, presented the results on behalf of the Austrian Breast & Colorectal Cancer Study Group here on December 15th at the 29th Annual San Antonio Breast Cancer Symposium (SABCS).The study involved 1,099 premenopausal women with estrogen- or progestin-receptor-positive, Stage I or II breast cancer. Following surgery, the women were randomized to 1 of 2 treatment regimens: 1) ovarian suppression with 3.6 mg of goserelin (Zoladex) every 28 days for 3 years and 20 mg/day of tamoxifen for 5 years; 2) 6 cycles of chemotherapy consisting of cyclophosphamide (Cytoxan) 600 mg/m2 combined with methotrexate 40 mg/m2, and fluorouracil (Adrucil) 600 mg/m2 intravenously on days 1 and 8. --Click the title of this post to read the full article from its source--

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